Dr. Trayanova holds the inaugural Murray B. Sachs Professorship in the Department of Biomedical Engineering at Johns Hopkins University. She is also a Professor of Medicine at the Johns Hopkins School of Medicine, and a Professor of Applied Mathematics and Statistics. She envisioned, created, and directs the Alliance for Cardiovascular Diagnostic and Treatment Innovation, a research enterprise aimed at bringing directly into the clinic innovative engineering and AI approaches to cardiovascular health. She is also the Director for AI Research in Health and Medicine at Johns Hopkins University under the Data Science and AI Institute, where she is responsible for directing efforts across the university in developing and deploying AI applications that advance healthcare delivery and improve patient outcomes. She also directs the Computational Cardiology Laboratory.

Dr. Trayanova is internationally recognized as the leader in multi-scale computational modeling of whole heart electrophysiology and arrhythmias. She has pioneered the development and use of clinical-image-based digital twins of patient hearts that faithfully represent the functioning of the patient’s diseased organ. Using her first-of-their-kind personalized heart digital twins and deep learning approaches, Dr. Trayanova has developed new technologies for accurately predicting risk of cardiac arrest and for the precise delivery of catheter ablation therapies in patients with heart rhythm disorders. For her pioneering work in computational cardiology, she has received NIH Director’s Pioneer Award. Her research output includes 450 published papers and book chapters. She has published extensively in the most prestigious journals, such as The Lancet, Nature Cardiovascular Medicine, Nature Communications, Nature BME, Science Advances, Science TM, Physiological Reviews, Nature Reviews Cardiology, eLife, and others.

Dr. Trayanova is the inventor on numerous patents and patent applications filed world-wide. In recognition of her innovation, she was named Fellow of the National Academy of Inventors in 2020. Trayanova’s work has received world-wide recognition, and she is the recipient of numerous honors and awards. In 2019, Dr. Trayanova was inducted in the Women of Technology International Hall of Fame, an honor conferred only on 5 women each year from around the world. Also in 2019, she received the Distinguished Scientist Award from Heart Rhythm Society. This was followed by the Zipes Distinguished Award by the same society in 2020, and by the Gordon Moe Award by the Cardiac Electrophysiology Society in 2023. In 2024 Trayanova was named the recipient of the Hodgkin-Huxley-Katz Award by the Physiological Society (to be bestowed in 2025). Trayanova has been named a Fellow of every American and European clinical cardiology society, testifying to her impact in clinical practice. She is also a Fellow of AIMBE, BMES, IAMBE, and IUPS. She has given over 380 invited lectures, majority of them keynotes or plenary lectures. Dr. Trayanova’s work has also received widespread media coverage and recognition, and she has also given a TEDx talk.