Donna Ryan is Professor Emerita at Pennington Biomedical in Baton Rouge, LA, USA where she had a 25-year career in clinical research in obesity. She was an Investigator on POUNDS Lost, Look AHEAD, DPP, DASH and many other studies of the health benefits of weight loss by diet, lifestyle intervention and medications. She was PI of a series of studies over 25 years funded by the US Department of Defense targeting military nutrition. Her personal research studied improving primary care management of obesity. She has been an active member and former President of The Obesity Society (North America) and World Obesity Federation. Currently Dr. Ryan serves as Co-Chair of the SELECT Steering Committee and member of the Data Safety Monitoring Boards for setmelanotide and retatrutide. She has more than 300 publications, is a frequent speaker on obesity and diabetes treatments and remains an active consultant and advisor to companies developing drugs, devices, lifestyle programs and medical approaches to obesity management.